
Health Management Center, Xiangya Hospital, Central South University, Changsha, China (J.W.)
Division of Rheumatology, Allergy, and Immunology, Department of Medicine, and the Mongan Institute, Massachusetts General Hospital, Harvard Medical School, Boston, Massachusetts (H.K.C., Y.Z.)
Section of Rheumatology, Boston University School of Medicine, Boston, Massachusetts (T.N.)
Department of Medicine, University of Auckland, Auckland, New Zealand (N.D.)
Rheumatology, Allergy-Immunology Section, San Diego VA Medical Center, San Diego, California (R.T.)
Department of Medicine, University of Otago, Christchurch, New Zealand (L.K.S.)
Department of Orthopedics, General Hospital of Chinese PLA, Beijing, and Department of Orthopaedics, Xiangya Hospital, Central South University, Changsha, China (H.L.)
Division of Rheumatology, Allergy, and Immunology, Department of Medicine, and the Mongan Institute, Massachusetts General Hospital, Harvard Medical School, Boston, Massachusetts, and Arthritis Research Canada, Richmond, British Columbia, Canada (N.M.)
Selzman Institute for Kidney Health, Section of Nephrology, Department of Medicine, Baylor College of Medicine, Houston, Texas (J.N.)
Department of Orthopaedics, Xiangya Hospital, Central South University, and Hunan Key Laboratory of Joint Degeneration and Injury, and National Clinical Research Center of Geriatric Disorders, Xiangya Hospital, Central South University, Changsha, China (C.Z.)
Department of Orthopaedics, Xiangya Hospital, Central South University, and National Clinical Research Center of Geriatric Disorders, Xiangya Hospital, Central South University, and Hunan Key Laboratory of Joint Degeneration and Injury, Changsha, China (G.L.).
Disclaimer: The interpretation of these data is the sole responsibility of the authors. THIN is a registered trademark of Cegedim SA in the United Kingdom and other countries. Reference made to the THIN database is intended to be descriptive of the data asset licensed by IQVIA. This work uses deidentified data provided by patients as a part of their routine primary care.
Financial Support: By the Project Program of National Clinical Research Center for Geriatric Disorders (Dr. Zeng: Xiangya Hospital 2020LNJJ03), the National Natural Science Foundation of China (Dr. Lei: 81930071 and 81772413, Dr. Zeng: 82072502), and the National Institutes of Health (Dr. Neogi: K24 AR070892 and P30 AR072571).
Disclosures: Disclosures can be viewed at www.acponline.org/authors/icmje/ConflictOfInterestForms.do?msNum=M21-2347.
Reproducible Research Statement:Study protocol: Available from Dr. Lei (e-mail, [email protected]edu.cn). Statistical code: See Supplement section 2. Data set: Available for purchase from [email protected]co.uk.
Corresponding Author: Guanghua Lei, MD, PhD, Department of Orthopaedics, Xiangya Hospital, Central South University, 87 Xiangya Road, Changsha, Hunan, China 410008; e-mail, [email protected]edu.cn; Yuqing Zhang, DSc, Division of Rheumatology, Allergy, and Immunology, Department of Medicine, Massachusetts General Hospital, Harvard Medical School, 55 Fruit Street, Boston, MA 02114; e-mail, [email protected]harvard.edu.
Author Contributions: Conception and design: H.K. Choi, G. Lei, J. Niu, J. Wei, Y. Zhang.
Analysis and interpretation of the data: H.K. Choi, N. Dalbeth, H. Lyu, N. McCormick, T. Neogi, L.K. Stamp, R. Terkeltaub, J. Wei, C. Zeng, Y. Zhang.
Drafting of the article: H.K. Choi, N. Dalbeth, T. Neogi, J. Niu, R. Terkeltaub, J. Wei, C. Zeng, Y. Zhang.
Critical revision of the article for important intellectual content: H.K. Choi, N. Dalbeth, G. Lei, H. Lyu, N. McCormick, T. Neogi, L.K. Stamp, R. Terkeltaub, C. Zeng, Y. Zhang.
Final approval of the article: H.K. Choi, N. Dalbeth, G. Lei, H. Lyu, N. McCormick, T. Neogi, J. Niu, L.K. Stamp, R. Terkeltaub, J. Wei, C. Zeng, Y. Zhang.
Provision of study materials or patients: H.K. Choi, G. Lei.
Statistical expertise: H.K. Choi, H. Lyu, T. Neogi, J. Niu, J. Wei, Y. Zhang.
Obtaining of funding: G. Lei, H. Lyu, C. Zeng.
Administrative, technical, or logistic support: H.K. Choi, G. Lei, Y. Zhang.
Collection and assembly of data: H. Lyu, J. Wei.
This article was published at Annals.org on 25 January 2022.